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Taking painkillers after a hangover can help reduce headaches and other unpleasant symptoms. Below are a few popular painkillers that are sometimes used after a hangover:

Aspirin (acetylsalicylic acid)

Taking aspirin (acetylsalicylic acid) after a hangover can help reduce headache and inflammation. However, dosage recommendations should be followed and contraindications and possible side effects should be considered. Here is some information about aspirin dosage, contraindications, and side effects:

Dosage:

• The usual dose of aspirin for headache or fever relief is 325-650 mg (1-2 tablets) every 4-6 hours as needed.
• For hangovers, it is usually recommended to take one or two aspirin tablets with plenty of water.

Contraindications:

• Aspirin is contraindicated for people who are allergic to acetylsalicylic acid or other drugs containing aspirin.
• It should be avoided if you have a stomach ulcer, gastrointestinal bleeding or other gastrointestinal problems.
• Aspirin is not recommended in pregnancy, especially close to the time of delivery, and during breastfeeding.

Side effects:

• Although effective, aspirin can irritate the mucous membranes of the stomach and intestines, which can lead to ulcers or bleeding.
• Other possible side effects include dizziness, nausea, vomiting, and allergic reactions.

It is important to follow dosage recommendations and not to take aspirin on an empty stomach to reduce the risk of irritation of the gastric mucosa. If you have any doubts or concerns about using aspirin, it is best to consult your doctor or pharmacist, especially if you have any medical conditions or medications you are taking that may interact with aspirin.

Paracetamol

Paracetamol can be used to relieve headaches and fever after a hangover, but it should be used with caution and follow dosage and safety guidelines. Here is information on the dosage, contraindications and side effects of paracetamol:

Paracetamol dosage after a hangover:

• For adults: It is generally recommended to take 500-1000 mg of paracetamol (1-2 500 mg tablets) every 4-6 hours as needed.
• The maximum daily dose for adults is usually 4000 mg (4 g), which is 8 500 mg tablets or 4 1000 mg tablets over 24 hours.
• It is important to observe the intervals between doses and not to exceed the maximum daily dose.

Contraindications of paracetamol:

• Allergic reaction to paracetamol or other ingredients of the medicine.
• Liver failure or liver disease.
• Alcohol intoxication or drinking alcohol in large quantities.
• Taking other medicines containing paracetamol.

Side effects of paracetamol:

• Paracetamol is usually well tolerated at the correct dosage, but may cause rare allergic reactions including skin rash and itching.
• An overdose of paracetamol can lead to severe liver damage, which is a serious condition.

Analgin

Analgin (metamizole) is a medicine that has analgesic, antipyretic and anti-inflammatory effects. It can be used to relieve headaches or muscle pain that sometimes occurs after drinking alcohol. However, it is worth noting that analgin will not help restore fluid and electrolyte levels that may have been lost as a result of a hangover and is not a specific hangover cure.

The dosage of analgin usually depends on the age and condition of the patient, as well as on the instructions provided by the doctor or on the drug package. It is recommended to strictly follow the dosage recommendations given in the instructions for the drug.

Contraindications to the use of analgin may include the following conditions and situations:

1. Individual intolerance to metamizole. Some people may be allergic to this drug.
2. Renal or hepatic dysfunction. The drug should be used with caution in people with these conditions.
3. Pregnancy and breastfeeding: In some cases, the use of analgin may be undesirable during pregnancy or breastfeeding.
4. Alcohol: It is not recommended to take analgin at the same time with alcohol, as this may increase the negative effects on the liver and kidneys.

Side effects of analgin may include allergic reactions, dyspeptic disorders (vomiting, nausea, diarrhea), and in rare cases bleeding or disorders of hematopoiesis. If you experience any side effects after taking analgin, it is recommended that you consult your doctor immediately.

Remember that analgin is a medication and should only be taken as prescribed by your doctor and as recommended on the package or in the instructions.

Citramon

Citramon is often used to relieve headache and other symptoms after a hangover. Its mechanism of action in this context is related to the components of the drug and the following processes:

1. Acetylsalicylic acid (aspirin): This ingredient has anti-inflammatory and analgesic properties. It may help reduce inflammation and head pain.
2. Paracetamol: Paracetamol also has analgesic properties and can reduce pain and fever (increased body temperature), which can occur after drinking alcohol.
3. Caffeine: Caffeine is a central nervous stimulant that can improve wakefulness and reduce feelings of fatigue, which can also be helpful for hangovers.

The dosage of citramone for hangovers is usually 1-2 tablets taken with plenty of water. This is usually done to relieve headaches, feelings of fatigue and other unpleasant symptoms that may accompany a hangover. However, it is important to follow the maximum daily dose indicated on the package or recommended by your doctor.

Contraindications to citramone include the following conditions:

• Hypersensitivity or allergic reaction to the components of the drug (aspirin, paracetamol, caffeine).
• Peptic ulcer disease of the stomach or duodenum.
• Increased bleeding or clotting disorders.
• Pregnancy and breastfeeding (especially in the case of codeine, if it is present in the drug).
• Liver or kidney failure.
• Children under 12 years of age.

Side effects of citramone may include stomach irritation, gastritis, gastrointestinal bleeding, allergic reactions and others. The caffeine in citramone can cause nervousness, insomnia, and palpitations.

It is important to remember that drinking alcohol and citramone at the same time can be harmful to your body and increase health risks.

Spasmalgon

"Spasmalgon" is a medicine that contains the active ingredient metamizole sodium (analgin), as well as pithophenone and phenylbutazone. It is used to relieve pain and spasms, and may sometimes be used after a hangover to relieve headaches and other symptoms. Here is information about Spasmalgon's mechanism of action, dosage, contraindications, and side effects:

Mechanism of Action:

• Metamizole sodium (analgin) is an analgesic and antipyretic. It works by reducing pain signals in the nervous system and lowering body temperature.
• Pitofenone and phenylbutazone are myorelaxants that help relax muscles and eliminate spasms.

Spazmalgon dosage:

• Dosage may vary depending on package instructions and doctor's recommendations.
• It is usually recommended that adults take 1-2 tablets of "Spasmalgon" 2-3 times a day after meals.
• It is not recommended to exceed the maximum daily dose.

Contraindications of "Spazmalgon":

• Allergic reaction to the components of the drug.
• Renal failure.
• Liver failure.
• Alport syndrome (kidney disorder).
• Structural changes in the blood (e.g., agranulocytosis).
• Pregnancy (especially in the first and third trimesters) and breastfeeding period.

Spazmalgon side effects:

• Side effects may include allergic reactions, dyspeptic symptoms (digestive disorders), blood changes, decreased blood pressure, and others.
• Side effects associated with the components of metamizole may also occur, such as rare allergic reactions including skin rash, itching, and even anaphylactic shock.

Before using Spasmalgon or any other medication after a hangover, be sure to consult your doctor to make sure it is safe for you, especially if you have any medical problems or are taking other medications.

Nurofen (ibuprofen)

Nurofen (ibuprofen) is another type of pain reliever that is sometimes used after a hangover to relieve headaches and other symptoms. Here's how ibuprofen works, along with information on dosage, contraindications, and side effects:

Mechanism of Action: Ibuprofen is an anti-inflammatory and analgesic drug that helps reduce inflammation and block pain signals in the body. It can also reduce fever (high temperature).

Dosage: The recommended adult dosage of ibuprofen for hangovers is usually 200-400 mg (1-2 tablets) every 4-6 hours as needed. It is not recommended to exceed the maximum daily dose (usually 1200-1600 mg).

Contraindications:

• Ibuprofen is contraindicated for people who are allergic to ibuprofen or other drugs in the group of nonsteroidal anti-inflammatory drugs (NSAIDs).
• It should be avoided if you have a stomach ulcer, gastrointestinal bleeding or other gastrointestinal problems.
• Not recommended in pregnancy (especially in the second and third trimesters) and during breastfeeding.

Side effects:

• Side effects may include stomach and intestinal irritation, nausea, vomiting, heartburn, gas, and diarrhea.
• Long-term and excessive use of ibuprofen may be associated with a risk of damage to the stomach, kidneys, and other organs.

It is important to adhere to dosage recommendations and not consume ibuprofen on an empty stomach to reduce the risk of gastric mucosal irritation.

Nimesil

"Nimesil (a cyclooxygenase inhibitor) can be used to relieve hangover headaches due to its ability to reduce inflammation and relieve pain. Here is the mechanism of action and information on dosage, contraindications and side effects for Nimesil:

Mechanism of action: Nimesil contains the active substance nimesulide, which is an anti-inflammatory and analgesic agent. It blocks the enzyme cyclooxygenase (COX), which leads to a decrease in the production of inflammatory mediators such as prostaglandins. This can help reduce inflammation and pain.

Dosage: The dosage of Nimesil may vary depending on your age, weight, and medical condition. Be sure to follow the instructions provided on the package or as directed in your doctor's prescription. Do not exceed the recommended dose.

Contraindications:

Before taking Nimesil, it is important to consider the following contraindications:

• Hypersensitivity: You should not use the drug if you have an allergic reaction to nimesulide or other components of the medicine.
• Pepticulcer disease: Use of Nimesil may increase the risk of ulcer exacerbation.
• Pregnancy and lactation: "Nimesil" is not recommended during pregnancy and lactation.
• Liver and kidney diseases: The drug may have adverse effects on the liver and kidneys, so you should consult your doctor if you have the corresponding diseases.

Side effects:

Side effects of Nimesil may include the following:

• Dyspeptic disorders (nausea, vomiting, diarrhea).
• Headache.
• Gastrointestinal bleeding.
• Allergic Reactions.
• Increased risk to the liver and kidneys.

If you experience any unwanted effects while taking Nimesil, contact your doctor.

No-Spah

"No-casp, or Drotaverine, is a medication that is often used to relieve pain and cramps in the stomach and intestines. It can be useful for some hangover symptoms, but it is not a direct hangover cure. Here's how it can affect and how to use it for hangovers:

Mechanism of action: Drotaverine acts as a myotropic antispasmodic by dilating blood vessels and relieving smooth muscle spasms. This may help improve circulation and reduce pain or discomfort in the stomach and intestines.

Dosage: The dosage of Drotaverine usually depends on individual needs and your doctor's recommendations or instructions for the drug. It is common to take 40-80 mg of Drotaverine up to three times a day. However, when using Drotaverine to relieve hangover symptoms, the dosage listed on the package or recommended by your doctor should be followed.

Contraindications: Drotaverine is not recommended for the following conditions:

• Known individual intolerance to the drug.
• Serious liver or kidney disease.
• Low blood pressure.

Side effects: Drotaverine is usually well tolerated and side effects are rare. Possible side effects may include headache, nausea, or rarely allergic reactions.

If you have symptoms of a hangover, including stomach or bowel pain, you can consult your doctor or pharmacist to find out if Drotaverine is right for you and at what dosage you should take it. However, the best way to avoid hangovers will always be to drink alcohol in moderation and drink enough water.

Antipohmelin

Antipolhmelin (Antipolhmelin) is a medicine that can be used to relieve hangover symptoms and improve the general condition after drinking alcohol. It contains several active ingredients such as acetylsalicylic acid (aspirin), anticellulose and ammonium.

These are the components that fulfill the functions in Antipohmelin:

1. Acetylsalicylic acid (aspirin): This ingredient may help relieve headaches and inflammation that may occur after drinking alcohol. Aspirin may also reduce the risk of blood clots because it is an antiplatelet agent.
2. Ammoniaca: Ammoniaca may have mild antihypertensive and diuretic effects. It may help flush some toxins out of the body.
3. Anti-cellulose: This ingredient can be used as a filler in tablets.

"Antipohmelin" is used to relieve hangover symptoms such as headache, nausea, vomiting and stomach discomfort. However, before using this medication or any other medication, it is important to consult your doctor or pharmacist, especially if you have medical contraindications, allergies, or are taking other medications.

Also remember that the best way to prevent hangovers is to drink alcohol in moderation and behave responsibly when drinking alcoholic beverages.

Upsarin (Upsa)

Upsarin (or Upsa) is a brand name for the drug metamizole sodium, which is used as an analgesic and antipyretic. It can be used to relieve some hangover symptoms such as headache or body aches, but should be taken with caution and according to your doctor's instructions or the instructions on the package. Here is general information about the mechanism of action, dosage, contraindications and side effects of methamizole:

Mechanism of Action:

• Metamizole is an analgesic and antipyretic agent. It has an analgesic (anti-pain) effect by blocking certain biochemical processes associated with the transmission of pain signals.

Dosage:

• The dosage of metamizole may depend on the patient's age, weight, and health status, as well as the reason for taking it.
• To treat headache or body aches, adults are usually advised to take 500 mg to 1,000 mg (half to one tablet) of metamizole up to three times a day after meals.
• The dosage for children should be determined by a doctor based on their age and weight.

Contraindications:

• Metamizole is contraindicated in case of known individual intolerance to this drug, as well as in case of past allergic reactions to it.
• It is also not recommended for use in bone marrow diseases, disorders of hematopoiesis, kidney and liver diseases, agranulocytosis (a decrease in the number of neutrophils in the blood), bronchial asthma, pregnancy (especially in the first and third trimesters) and during lactation.

Side effects:

• Methamizole side effects may include allergic reactions, liver dysfunction, kidney dysfunction, decreased white blood cell count, hypotension (low blood pressure), etc.

Taking metamizole to relieve hangover symptoms may relieve some unpleasant sensations, but it should be remembered that it does not treat the hangover itself and does not eliminate its cause. Also, the use of metamizole should be done in accordance with the doctor's recommendations or the instructions on the package to avoid possible unwanted side effects and contraindications. It is important not to abuse the medication for hangovers and consult a doctor if necessary.

Solpadeine

Solpadeine is a combination medicine that contains paracetamol, caffeine and codeine. It is commonly used to relieve pain and headaches. Some people may also take it to relieve hangover symptoms such as headache and general malaise. Here's how its ingredients may work:

1. Paracetamol: Paracetamol has analgesic and antipyretic properties. It can help relieve pain and headaches that may occur after drinking alcohol.
2. Caffeine: Caffeine is a central stimulant and can help keep you awake and reduce the drowsiness that often accompanies hangovers.
3. Codeine: Codeine is an opioid agent and can help relieve more severe pain and general malaise.

Dosage: Solpadeine dosage may vary depending on the specific drug and your doctor's recommendations or package directions. It is important to follow the recommended dosage, as codeine can have potentially dangerous side effects if the dosage is exceeded.

Contraindications and side effects: Solpadeine may have contraindications and side effects, including the potential for addiction due to the codeine content. Side effects may include drowsiness, nausea, constipation, and others. You should not increase the dose or use solpadeine for an extended period of time without consulting your doctor. Make sure you have no medical contraindications for taking it and consult your doctor before using it to relieve hangover symptoms.

Pentalgin

"Pentalgin" is a combination drug containing several active ingredients such as paracetamol, naproxen, caffeine and drotaverine. Usually, "Pentalgin" is used to relieve pain and inflammation and to relieve muscle spasms. It may also be used to relieve some hangover symptoms.

The mechanism of action of the components of "Pentalgin" in hangover:

1. Paracetamol: It has analgesic (pain relieving) and antipyretic properties that can help relieve headaches and fever that can accompany hangovers.
2. Naproxen: It is an anti-inflammatory drug and also has an analgesic effect, which can help relieve pain and inflammation.
3. Caffeine: Acts as a stimulant and can help you stay awake, which can be helpful for the fatigue and sleepiness that often accompany hangovers.
4. Drotaverine: A muscle relaxant that can help relieve cramps and spasms.

Pentalgin dosage and directions for use should follow the manufacturer's instructions and the directions of your doctor or pharmacist. Contraindications and side effects may be associated with each of the components and may vary from person to person. Therefore, it is important to follow the recommendations and not exceed the recommended dosage.